Holyoke grew up in Colorado and graduated college in Vermont. In fifth grade, she and her friend wrote a book called Rustlers of the High Country; though the book was never published, it inspired her to become a writer.
Prior to writing the Neptune Project books, she taught middle school social studies for eight years.
Holyoke is married.
She has two rescue Chihuahuas, a beagle, two cats, and a parakeet.
- Holyoke can read French.